New compounds could help treat memory problems in depression. Memory loss can happen with age or in case of mental health issues such as depression. Now scientists have come up with new compounds that could alter this cognitive effect.
People with emotional distress or condition like depression can also suffer from memory problems. A past study published in the journal Neurology found that people who were experiencing symptoms of depression also suffered from poor episodic memory, the memory of past personal experiences.
In a new study, scientists from Toronto’s Centre for Addiction and Mental Health in Canada wanted to develop new compounds that could reverse memory loss associated with depression and age progression.
“Currently, there are no medications to treat cognitive symptoms such as memory loss that occur in depression, other mental illnesses, and aging,” study author Dr. Etienne Sibille noted.
Dr. Sibille and colleagues have published findings of their new discovery in the journal Molecular Neuropsychiatry. The team developed a series of molecules.
The researchers administered one dose of modified benzodiazepines compounds to mice that had stress-generated memory loss. The team found that memory task was at its normal condition after 30 minutes. They followed this treatment for a long time and observed the positive effects for more than 2 months.
“The aged cells regrew to appear the same as young brain cells, showing that our novel molecules can modify the brain in addition to improving symptoms,” said Dr. Etienne Sibille.
The researchers’ team also presented their findings at the Annual Meeting of American Association for the Advancement of Science in Washington, DC, earlier this week.
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